| 本书是一本探讨我们对癌症发生发展的知识，从而预测发生的危险程度，以及发生后经过治疗决定预后的各种可能因素的专著。该书系统回顾了近年来分子标记物、组织病理学和临床表现等综合治疗的进展，临床试验的数据以及精确的非线性数学和统计学失算的规范化治疗后果等资料，在最大限度上悼念了病人生物数据，以建立一种预测病人预后的模式，这对于临床上如何处理病人具有决定性的重要意义。全书共分五个部分，每一部分都从不同的角度来讨论癌症结果预测的问题，具体内容包括临床难题、生物和遗传因素、预后模型的数学背景、机器学习方法的应用等。该书可供各大专院校作为教材使用，也可供从事相关工作的人员作为参考用书使用。 |
| Foreword Contributors Introduction Section 1 -The Clinical Problem Chapter 1 The Predictive Value of Detailed Histological Staging of Surgical Resection Specimens in Oral Cancer J.A.Woolgar Chapter 2 Survival after Treatment of Intraocular Melanoma B.E.Damato and A.F.G.Taktak Chapter 3 Recent Developments in Relative Survival Analysis T.R.Hakulinen and T.A.Dyba Section 2 - Biological and Genetic Factors Chapter 4 Environmental and Genetic Risk Factors of Lung Cancer A.Cassidy and J.K.Field Chapter 5 Chaos, Cancer, the Cellular Operating System and the Prediction of Survival in Head and Neck Cancer A.S.Jones Section 3 - Mathematical Background of Prognostic Models Chapter 6 Flexible Hazard Modelling for Outcome Prediction in Cancer: Perspectives for the Use of Bioinformatics Knowledge E.Biganzoli and P.Boracchi Chapter 7 Information Geometry for Survival Analysis and Feature Selection by Neural Networks A.Eleuteri, R.Tagliaferri, L.Milano and M.de Laurentiis Chapter 8 Artificial Neural Networks Used in the Survival Analysis of Breast Cancer Patients: A Node-Negative Study C.T.C.Arsene and EJ.G.Lisboa Section 4 - Application of Machine Learning Methods Chapter 9 The Use of Artificial Neural Networks for the Diagnosis and Estimation of Prognosis in Cancer Patients A.M.Marchevsky Chapter 10 Machine Learning Contribution to Solve Prognositic Medical Problems E Baronti, A.Micheli, A.Passaro and A.Starita Chapter 11 Classification of Brain Tumours by Pattern Recognition of Magnetic Resonance Imaging and Spectroscopic Data A.Devos, S.van Huffel, A.W.Simonetti, M.van der Graaf, A.Heerschap and L.M.C.Buydens Chapter 12 Towards Automatic Risk Analysis for Hereditary Non-Polyposis Colorectal Cancer Based on Pedigree Data M.Koktier, R.N.G.Naguib, E Jancovic, H.B.Younghusband and R.Green Chapter 13 The Impact of Microarray Technology in Brain Cancer M.G.Kounelakis, M.Zervakis and X.Kotsiakis Contents Section 5 - Dissemination of Information Chapter 14 The Web and the New Generation of Medical Information Systems J.M.Fonseca, A.D.Mora and P.Barroso Chapter 15 Geoconda: A Web Environment for Multi-Centre Research C.Setzkom, A.F.G.Taktak and B.E.Damato Chapter 16 The Development and Execution of Medical Prediction Models M.W.Kattan, M.G6nen and P.T.Scardino Index |
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